Road closures set to take place to prepare for construction of new UK Healthcare facility

A map of Lexington, KY featuring roads around the hospital system with red lines denoting which ones will be closed for construction

The red lines show where roads will be closed through September 2025. | Map via Google Maps

As if traffic on Limestone + Nicholasville Road didn’t already drive you wild — it’s about to get a little more challenging.

In order to prepare for construction of the new eight-story, 550,000-sqft cancer and advanced ambulatory facility + parking garage, major roadwork will take place on surrounding streets.

Beginning in April, expect the following traffic delays:

  • Elizabeth Street will close to thru traffic
  • State Street + University Avenue will close from Elizabeth Street to South Limestone
  • A fence will go up, prohibiting pedestrian traffic

When the work is completed, estimated around September 2025, this is what things will look like:

  • A continuous four-lane road with a turning lane from Waller Avenue to Transcript Avenue
  • Two lanes from Transcript Avenue to Virginia Avenue
  • Overhead utility lines moved underground

Keep in mind, the work will be reconfiguring and revising the roads as they are currently placed.

More from LEXtoday
These projects top Zillow’s list for home upgrades that could deliver the strongest return when it’s time to sell.
From brands to artists, Lexington’s business scene is truly inspired.
Crave Taco Week runs Monday, March 9 to Sunday, March 15, where you can try out dozens of tacos from 20+ different restaurants.
Support local organizations by cleaning out your closets and cabinets.
Bookmark this guide for a curated list of events taking place each month that we’re most looking forward to.
Move aside pickleball, there’s a new racket sport in town.
Put your money where your community is and help us create a guide to small businesses by submitting your favorite local spots and sharing this page with a friend.
We’re highlighting the 23 best parks that Lexington, KY has to offer — complete with splash pads, playgrounds, walking trails, and even a few dog-friendly spots.
A veteran turns to bourbon, mindfulness, and storytelling to navigate PTSD and find purpose.
Discover expert tips and all the supplies you need to dive into your next stitching project.